# Our recommendations for giving in 2021

You can have a remarkable impact by supporting cost-effective, evidence-based charities.

Just looking at the approximately $100 million GiveWell had discretion to grant in 2020—a subset of all the money we directed to the charities we recommend—the impact of our donors is impressive. We estimate these grants will: • Save more than 24,000 lives • Treat over 6 million children with a full course of antimalarial medication • Provide vitamin A supplementation to over 8.6 million children • Deliver over 4.4 million long-lasting insecticide-treated nets (LLINs) to protect against malaria • Vaccinate 118,000 children • Treat over 11.4 million children for parasitic worms Read More # Initial thoughts on malaria vaccine approval The World Health Organization (WHO) recently recommended the widespread use of the malaria vaccine RTS,S/AS01 for children. It provides an additional, effective tool to fight malaria. This is great news! We’ve been following this vaccine’s development for years and, in the last few months, have been speaking with organizations involved in its development and potential wider rollout. Our work on RTS,S (and other malaria vaccines) is ongoing, and we might significantly update our views in the near future. But because we’ve been following its progress, we’re sharing some initial thoughts. Read More # Our recommendations for giving in 2020 You can have a major, positive impact today by choosing to support organizations backed by strong evidence: our top charities. We recommend the nonprofits that offer the most impact per dollar we’re aware of. In fact, we estimate that you can save a life by donating$3,000-$5,000 to our top recommendation.[1] If you’re a longtime donor, you’ll recognize most of this year’s top charities. You may even wonder why our list hasn’t changed much. However, a tremendous amount of research—truly thousands of hours—has been done to ensure that these organizations continue to meet our high standards. And although there are many familiar names, one is entirely new: New Incentives. We’re proud to share our recommendations and grateful to you for considering supporting them. We hope you’ll read on! Read More # Maximum Impact Fund update: Q1 and Q2 2020 Thanks to our donors, we have disbursed$23.3 million in flexible funding to our top charities this year. This generous, flexible support is worthy of celebration!

This post focuses on our decision to grant $15.3 million to the Against Malaria Foundation (AMF), which includes the$11.7 million that donors gave to “Grants to recommended charities at GiveWell’s discretion” in the first half of 2020.[1]

AMF supports the distribution of insecticide-treated nets in areas with high rates of malaria. The nets stop mosquitoes from biting and spreading the disease. We estimate our donors’ support for AMF will collectively save over 3,000 lives, mostly of young children in the Democratic Republic of the Congo (DRC) and Guinea.[2] Without this grant, we think net distributions in DRC and Guinea would have been delayed.

We believe that AMF was the highest-impact choice for this grant. We chose AMF after assessing the effect of the COVID-19 pandemic on our top charities, the urgency of our top charities’ funding needs, and our estimates of their impact per dollar. We’re grateful for GiveWell donors’ trust in providing flexible funding to fill this need.

# Why we’re excited to fund charities’ work a few years in the future

We recently spoke with someone who wanted to donate to a GiveWell top charity. They were interested in getting the funding “out the door” and to program participants as quickly as possible.

But our top choice for funding today is Malaria Consortium’s seasonal malaria chemoprevention program—for work it expects to complete in 2022.[1] The potential donor was puzzled. Shouldn’t we prioritize an organization that needs the money sooner?

We often recommend donations today that support programs a few years from now. This probably diverges from many people’s intuitions about getting funding out the door as soon as possible.

# GiveWell donors supported more than direct delivery: AMF and new net research

Supporters of the Against Malaria Foundation in recent years may have had even more impact than they expected.

The Against Malaria Foundation (AMF) is a GiveWell top charity because we believe its program to distribute insecticide-treated nets prevents people from dying of malaria. AMF-supported net distributions are incredibly cost-effective; we estimate that a \$2,000-3,000 donation averts one death.[1] AMF’s work is important in and of itself to fund.

Not all AMF donations, however, just support typical net distributions. In recent years, AMF supported research on a new type of insecticide-treated net, the piperonyl butoxide (PBO) net. This research itself (i.e., researcher time, equipment, and administrative costs) was funded by a small number of AMF donors who explicitly agreed to support it. The research was conducted on nets that were contributed by a broad group of AMF donors.

Preliminary data suggest that PBO nets are more effective at preventing malaria than standard insecticide-treated nets in areas where mosquitoes have developed insecticide resistance. We think it is likely that AMF sped up the completion of a large-scale, high-quality study of these new nets.

We’re thrilled to recommend charities that contribute research in the fields in which they operate. AMF doesn’t just prevent deaths from malaria by distributing nets—it has improved our and others’ understanding of which nets can work best in the future. This post is to share this story with our donors, whose contributions make this work possible.

## Summary

In this post, we’ll discuss:

• Insecticide resistance and the potential of PBO nets. (More)
• AMF’s role in PBO net research. (More)