The GiveWell Blog

Research Strategy: Vaccines

GiveWell started supporting vaccines in 2015 and has made over $160 million in grants to date. With strong results from past work in this space, we’re now exploring how to reach more people with vaccines in low- and middle-income countries. This post discusses our current thinking on vaccines grantmaking and our key hypotheses about where to focus our efforts going forward.

Where are we now?

Before this year, our grants for vaccine programs focused on (a) increasing uptake of the vaccines given to children in the first two years of life, and (b) speeding up the rollout of malaria vaccines.

Relative to other global health approaches, vaccines garner a lot of attention. Governments in high-income countries contribute to Gavi, the Vaccine Alliance, which heavily subsidizes the purchasing of vaccines in the world’s poorest countries and provides cash assistance to help these countries deliver them. The Gates Foundation is also a major contributor to vaccine programs. These efforts have been fairly successful—in 2022, 81% of children in the 57 low-income countries supported by Gavi had received the DTP3 vaccine, which protects against diphtheria, tetanus, and pertussis. DTP3 coverage is often used as a benchmark for progress on vaccination.

This provides both a challenge and an opportunity for finding cost-effective giving opportunities. On the one hand, thankfully, the people who are easiest to reach with vaccines are already being reached, which means more expensive or innovative methods are needed to expand coverage. On the other hand, we can build on the extensive knowledge and infrastructure that already exists.

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Allocation of discretionary funds from Q2 2018

In April to June 2018, we received $1.2 million in funding for making grants at our discretion. In addition, GiveWell’s Board of Directors voted to allocate $2.9 million in unrestricted funds to making grants to recommended charities. In this post we discuss:

  • The decision to allocate the $4.1 million to the Against Malaria Foundation (AMF) (70 percent) and the Schistosomiasis Control Initiative (SCI) (30 percent).
  • Our recommendation that donors give to GiveWell for granting to top charities at our discretion so that we can direct the funding to the top charity or charities with the most pressing funding need. For donors who prefer to give directly to our top charities, we continue to recommend giving 70 percent of your donation to AMF and 30 percent to SCI to maximize your impact.
  • Why we have allocated unrestricted funds to making grants to recommended charities.

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Allocation of discretionary funds from Q1 2018

In the first quarter of 2018, we received $2.96 million in funding for making grants at our discretion. In this post we discuss:

  • The decision to allocate the $2.96 million to the Against Malaria Foundation (AMF) (70 percent) and the Schistosomiasis Control Initiative (SCI) (30 percent).
  • Our recommendation that donors give to GiveWell for granting to top charities at our discretion so that we can direct the funding to the top charity or charities with the most pressing funding need. For donors who prefer to give directly to our top charities, we continue to recommend giving 70 percent of your donation to AMF and 30 percent to SCI to maximize your impact.

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Allocation of discretionary funds from Q4 2017

In the fourth quarter of 2017, we received $5.6 million in funding for making grants at our discretion. In this post we discuss:

  • The decision to allocate the $5.6 million to the Schistosomiasis Control Initiative (SCI).
  • Our recommendation that donors give to GiveWell for granting to top charities at our discretion so that we can direct the funding to the top charity or charities with the most pressing funding need. For donors who prefer to give directly to our top charities, we continue to recommend giving 70 percent of your donation to AMF and 30 percent to SCI to maximize your impact.

We noted in November that we would use funds received for making grants at our discretion to fill the next highest priority funding gaps among our top charities. We also noted that our best guess at the time was that we would give 70 percent to the Against Malaria Foundation (AMF) and 30 percent to SCI.

Based on information received since November, described below, we allocated the $5.6 million to SCI, rather than dividing these funds between AMF and SCI, as previously expected. GiveWell’s Executive Director, Elie Hassenfeld, the fund advisor on the Effective Altruism Fund for Global Health and Development also recommended that the fund grant out the $1.5 million that it held to SCI.

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GiveWell’s money moved and web traffic in 2016

In September 2017, we posted an interim update on GiveWell’s 2016 money moved and web traffic. This post summarizes the key takeaways from our full 2016 money moved and web traffic metrics report. Note that some of the numbers, including the total headline money moved, have changed since our interim report. Since then, we decided to exclude some donations from our headline money moved figure (details in the full report), and we corrected some minor errors.

This report was highly delayed (as discussed in the interim update). We expect to publish our report on GiveWell’s 2017 money moved and web traffic much more quickly; our current expectation is that we will publish that report by the end of June.

GiveWell is dedicated to finding outstanding giving opportunities and publishing the full details of our analysis. In addition to evaluations of other charities, we publish substantial evaluation of our own work. This post lays out highlights from our 2016 metrics report, which reviews what we know about how our research impacted donors.

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Our top charities for giving season 2017

This year, we added two new top charities, Evidence Action’s No Lean Season program and Helen Keller International’s vitamin A supplementation program, and retained our seven top charities from 2016. We also added Evidence Action’s Dispensers for Safe Water program to our list of standout charities.

We recommend that donors give to GiveWell for granting to top charities at our discretion so that we can direct the funding to the top charity or charities with the most pressing funding need. For donors who prefer to give directly to our top charities, we recommend giving 70 percent of your donation to the Against Malaria Foundation (AMF) and 30 percent to the Schistosomiasis Control Initiative (SCI) to maximize your impact. We expect Good Ventures, a foundation with which we work closely, to provide significant support to each top charity; our recommendation to give to AMF and SCI is based on how much good we believe additional donations can do.

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